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1.
Acta otorrinolaringol. cir. cuello (En línea) ; 51(2): 137-142, 20230000. ilus
Artigo em Espanhol | LILACS, COLNAL | ID: biblio-1442499

RESUMO

Introducción: el papel clave del olfato, antiguo sistema sensorial, es proporcionar información sobre las sustancias químicas en el medio ambiente. El olfato desempeña un papel en la detección de compuestos peligrosos, el mantenimiento de la nutrición, el comportamiento interpersonal, la salud neurológica y la sensación de placer, entre otras funciones. En consecuencia, la disfunción olfativa puede conducir a un riesgo de lesiones, desnutrición, aislamiento social y una mala calidad de vida. Materiales y métodos: se realizó una exploración bibliográfica y se identificaron artículos de acuerdo con los criterios de inclusión y exclusión definidos y se tomaron aquellos con calidad en la evidencia. Discusión: el sistema olfativo humano tiene diferencias anatómicas, fisiológicas y genéticas considerables con respecto al de otros mamíferos. Conclusiones: las destrezas olfativas varían con factores como la edad, el sexo, la etapa de desarrollo, ciertas enfermedades otorrinolaringológicas y enfermedades generales.


Introduction: The key role of the ancient olfactory sensory system is to provide information about chemicals in the environment. Smell plays a role in the detection of dangerous compounds, the maintenance of nutrition, interpersonal behavior, neurological health, and the sensation of pleasure, among other functions. Consequently, olfactory dysfunction can lead to a risk of injury, malnutrition, social isolation, and a poor quality of life. Materials and methods: A bibliographical exploration was carried out and articles were identified according to the inclusion and exclusion criteria defined and those with quality evidence were taken. Discussion: The human olfactory system has considerable anatomical, physiological, and genetic differences from that of other mammals. Conclusions: Olfactory skills vary with factors such as age, sex, stage of development, certain ear, nose and throat diseases and general diseases.


Assuntos
Humanos , Masculino , Feminino , Olfato , Otorrinolaringologistas , Nervo Olfatório , Receptores Odorantes
2.
Biomed Res Int ; 2014: 346873, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24895567

RESUMO

INTRODUCTION: We present our experience in the reconstruction of these leaks depending on their size and location. MATERIAL AND METHODS: Fifty-four patients who underwent advanced skull base surgery (large defects, >20 mm) and 62 patients with CSF leaks of different origin (small, 2-10 mm, and midsize, 11-20 mm, defects) were included in the retrospective study. Large defects were reconstructed with a nasoseptal pedicled flap positioned on fat and fascia lata. In small and midsized leaks. Fascia lata in an underlay position was used for its reconstruction covered with mucoperiosteum of either the middle or the inferior turbinate. RESULTS: The most frequent etiology for small and midsized defects was spontaneous (48.4%), followed by trauma (24.2%), iatrogenic (5%). The success rate after the first surgical reconstruction was 91% and 98% in large skull base defects and small/midsized, respectively. Rescue surgery achieved 100%. CONCLUSIONS: Endoscopic surgery for any type of skull base defect is the gold standard. The size of the defects does not seem to play a significant role in the success rate. Fascia lata and mucoperiosteum of the turbinate allow a two-layer reconstruction of small and midsized defects. For larger skull base defects, a combination of fat, fascia lata, and nasoseptal pedicled flaps provides a successful reconstruction.


Assuntos
Vazamento de Líquido Cefalorraquidiano/diagnóstico , Vazamento de Líquido Cefalorraquidiano/cirurgia , Endoscopia/métodos , Osteotomia/métodos , Procedimentos de Cirurgia Plástica/métodos , Base do Crânio/anormalidades , Base do Crânio/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Base do Crânio/patologia , Retalhos Cirúrgicos , Resultado do Tratamento , Adulto Jovem
3.
Acta otorrinolaringol. cir. cabeza cuello ; 41(1): 36-39, ene.-mar. 2013. ilus
Artigo em Espanhol | LILACS | ID: lil-694375

RESUMO

Los queloides son prominencias que se forman en la piel por crecimientos exagerados del tejido cicatricial en el sitio de una lesión cutánea, que pueden producirse por incisiones quirúrgicas, heridas traumáticas, sitios de vacunación, quemaduras, varicela, acné, radiación, colocación de piercings o incluso pequeñas lesiones o raspaduras. El presente estudio demuestra que la combinación de la resección quirúrgica y la aplicación tópica de mitomicina C es altamente efectiva para evitar la recurrencia de queloides en las orejas…


Keloids are skin lesions formed by an overgrowth of scar tissue at the site of injury may be caused by cutaneous surgical incisions, traumatic wounds, vaccination sites, burns, chickenpox, acne, radiation, piercings or even minor injuries or abrasions. Most keloids will flatten and become less noticeable over the years. Extensive keloids may limit the mobility of the hands, feet or limbs and cause aesthetic. The mitomycin A, B and C are a group of cytotoxic antibiotics and antibacterial properties derived from a common structure called mitosana and are produced by species of the genus Streptomyces. The mitomycin C is an antibiotic that was isolated and studied from Streptomyces caespitosus by Hata and other Japanese researchers in 1955 and 1958 by Wakaki and others.2-4 contains a urethane group and a quinone group in its structure and an aziridine ring, which is essential for the antineoplastic activity…


Assuntos
Humanos , Mitomicina , Queloide , Queloide/reabilitação
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